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 TB Drugs Protocol

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AuthorMessage
Roslan
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PostSubject: TB Drugs Protocol   Thu Oct 04, 2012 8:20 am









ANTI-TUBERCULOSIS
DRUGS

First line anti-TB drugs (loose forms)


1. Ethambutol
HCL 200 mg tablet, 400 mg tablet



Indication: In
combination with other anti-TB medications for TB treatment. For adults TB
cases only during Intensive Treatment Phase.






Dosage: Intensive Phase: 15 mg/kg of body weight
daily (maximum dose 1200 mg daily)






2. Isoniazid
100 mg tablet, 400 mg tablet



Indication: In
combination with other anti-TB medications for TB treatment. . For adults TB
cases during Intensive and Maintenance Treatment Phase






Dosage: Intensive Phase: 5 mg/kg of body weight
daily (maximum dose 300 mg daily)



Maintenance
Phase: 5mg/kg/day, max 300mg daily






3. Rifampicin
150 mg capsule, 300 mg capsule



Indication: In
combination with other anti-TB medications for TB treatment. For adults TB
cases during Intensive and Maintenance Treatment Phase.






Dosage: Intensive Phase: 10 mg/kg of body weight
daily (maximum dose 600 mg daily)



Maintenance Phase : 10 mg/kg of body weight daily
(maximum dose 600 mg daily)






4. Pyrazinamide
500 mg tablet



Indication: In
combination with other anti-TB medications for TB treatment. For adults TB
cases only during Intensive Treatment Phase.






Dosage: Intensive Phase: 25 mg/kg of body weight
daily (maximum dose 1500 mg daily)






First
line anti-TB drugs (Fixed Dose Combination) for Intensive Phase





1. Combination
of Rifampicin 150mg, Isoniazid 75 mg, Pyrazinamide 400mg, Ethambutol HCL 275 mg



Indication: For
treatment of adults TB patients only during Intensive Phase of treatment.



Dosage: - Based on body weight:


- 30-37
kg: 2 tablets daily



- 38-54 kg: 3 tablets daily


- 55-70kg: 4 tablets daily


- > 70 kg: 5 tablets daily






Pyridoxine (Vitamin B6)


1. Pyridoxine
(Vitamin B6) 10 mg tablet



Indication: Prophylaxis
against isoniazid neuropathy



Dosage: 20mg daily





Side effects of anti-TB drugs:


Major side effect

Minor side effect

Jaundice

Discolouration
of urine ( orange/yellow urine)


Persistent
vomiting


Mild
nausea with occasional vomiting


Visual
impairment


Abdominal
discomfort


Confusion

Lack
of energy


Skin
rash and itch


Mild
skin rash and itch




Joint
pain
















Original Post By : DR Marilyn Umar
UNIT TBCP / LEPROSI JKNS SARAWAK








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PostSubject: Re: TB Drugs Protocol   Wed Oct 24, 2012 1:39 am

panjang glak ya lan
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