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 TB Drugs Protocol

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AuthorMessage
Roslan
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PostSubject: TB Drugs Protocol   Thu Oct 04, 2012 7:20 am









ANTI-TUBERCULOSIS
DRUGS

First line anti-TB drugs (loose forms)


1. Ethambutol
HCL 200 mg tablet, 400 mg tablet



Indication: In
combination with other anti-TB medications for TB treatment. For adults TB
cases only during Intensive Treatment Phase.






Dosage: Intensive Phase: 15 mg/kg of body weight
daily (maximum dose 1200 mg daily)






2. Isoniazid
100 mg tablet, 400 mg tablet



Indication: In
combination with other anti-TB medications for TB treatment. . For adults TB
cases during Intensive and Maintenance Treatment Phase






Dosage: Intensive Phase: 5 mg/kg of body weight
daily (maximum dose 300 mg daily)



Maintenance
Phase: 5mg/kg/day, max 300mg daily






3. Rifampicin
150 mg capsule, 300 mg capsule



Indication: In
combination with other anti-TB medications for TB treatment. For adults TB
cases during Intensive and Maintenance Treatment Phase.






Dosage: Intensive Phase: 10 mg/kg of body weight
daily (maximum dose 600 mg daily)



Maintenance Phase : 10 mg/kg of body weight daily
(maximum dose 600 mg daily)






4. Pyrazinamide
500 mg tablet



Indication: In
combination with other anti-TB medications for TB treatment. For adults TB
cases only during Intensive Treatment Phase.






Dosage: Intensive Phase: 25 mg/kg of body weight
daily (maximum dose 1500 mg daily)






First
line anti-TB drugs (Fixed Dose Combination) for Intensive Phase





1. Combination
of Rifampicin 150mg, Isoniazid 75 mg, Pyrazinamide 400mg, Ethambutol HCL 275 mg



Indication: For
treatment of adults TB patients only during Intensive Phase of treatment.



Dosage: - Based on body weight:


- 30-37
kg: 2 tablets daily



- 38-54 kg: 3 tablets daily


- 55-70kg: 4 tablets daily


- > 70 kg: 5 tablets daily






Pyridoxine (Vitamin B6)


1. Pyridoxine
(Vitamin B6) 10 mg tablet



Indication: Prophylaxis
against isoniazid neuropathy



Dosage: 20mg daily





Side effects of anti-TB drugs:


Major side effect

Minor side effect

Jaundice

Discolouration
of urine ( orange/yellow urine)


Persistent
vomiting


Mild
nausea with occasional vomiting


Visual
impairment


Abdominal
discomfort


Confusion

Lack
of energy


Skin
rash and itch


Mild
skin rash and itch




Joint
pain



[center]













Original Post By : DR Marilyn Umar
UNIT TBCP / LEPROSI JKNS SARAWAK








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PostSubject: Re: TB Drugs Protocol   Wed Oct 24, 2012 12:39 am

panjang glak ya lan
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TB Drugs Protocol

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